Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
additional information | - |
gene sequence is used for protein structure prediction, model of ShKamB | Streptoalloteichus hindustanus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptoalloteichus hindustanus | Q2MEY3 | - |
- |
Synonyms | Comment | Organism |
---|---|---|
16S rRNA:m(1)A1408 methyltransferase | - |
Streptoalloteichus hindustanus |
KamB | - |
Streptoalloteichus hindustanus |
ShKam | - |
Streptoalloteichus hindustanus |
General Information | Comment | Organism |
---|---|---|
physiological function | microorganisms that produce aminoglycosides have developed a special mechanism of high level resistance by posttranscriptional methylation of 16S rRNA in the aminoglycoside binding site. N1-methylation of A1408 confers resistance to kanamycin, tobramycin, sisomycin and apramycin, but not to gentamycin. The M1A1408 methylation is carried out by methyltransferases from the Kam family | Streptoalloteichus hindustanus |