KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.019 | - |
2-(1-methylethylidine)succinate | - |
Saccharomyces cerevisiae | |
0.045 | - |
3-butylmalate | - |
Saccharomyces cerevisiae | |
0.053 | - |
trans-aconitate | - |
Saccharomyces cerevisiae | |
0.127 | - |
(2R,3S)-3-isopropylmalate | - |
Saccharomyces cerevisiae | |
0.323 | - |
isopropylmaleate | - |
Saccharomyces cerevisiae | |
0.341 | - |
(2S,3R)-3-isopropylmalate | - |
Saccharomyces cerevisiae | |
0.428 | - |
(2R,3R)/(2S,3S)-3-isopropylmalate | - |
Saccharomyces cerevisiae | |
1.67 | - |
isopropylfumarate | - |
Saccharomyces cerevisiae |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Saccharomyces cerevisiae | the enzyme may work in two different pathways in two different ways: for detoxification in the citric acid cycle and for a possibly novel biosynthetic branch reaction of the leucine biosynthetic pathway | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the enzyme may work in two different pathways in two different ways: for detoxification in the citric acid cycle and for a possibly novel biosynthetic branch reaction of the leucine biosynthetic pathway | Saccharomyces cerevisiae | ? | - |
? | |
additional information | no activity as substrate: 2-isopropylmalate | Saccharomyces cerevisiae | ? | - |
? | |
S-adenosyl-L-methionine + (2R,3R)/(2S,3S)-3-isopropylmalate | poor substrate | Saccharomyces cerevisiae | S-adenosyl-L-homocysteine + ? | - |
? | |
S-adenosyl-L-methionine + (2R,3S)-3-isopropylmalate | - |
Saccharomyces cerevisiae | S-adenosyl-L-homocysteine + ? | - |
? | |
S-adenosyl-L-methionine + (2S,3R)-3-isopropylmalate | - |
Saccharomyces cerevisiae | S-adenosyl-L-homocysteine + ? | - |
? | |
S-adenosyl-L-methionine + 2-(1-methylethylidine)succinate | - |
Saccharomyces cerevisiae | S-adenosyl-L-homocysteine + ? | - |
? | |
S-adenosyl-L-methionine + 3-butylmalate | - |
Saccharomyces cerevisiae | S-adenosyl-L-homocysteine + ? | - |
? | |
S-adenosyl-L-methionine + isopropylfumarate | poor substrate | Saccharomyces cerevisiae | S-adenosyl-L-homocysteine + ? | - |
? | |
S-adenosyl-L-methionine + isopropylmaleate | - |
Saccharomyces cerevisiae | S-adenosyl-L-homocysteine + ? | - |
? | |
S-adenosyl-L-methionine + trans-aconitate | - |
Saccharomyces cerevisiae | S-adenosyl-L-homocysteine + (E)-2-(methoxycarbonylmethyl)butenedioate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Tmt1 methyltransferase | - |
Saccharomyces cerevisiae |