Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli BL21(DE3)pLysS cells | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
additional information | an exon-4 and -5 skipping (DELTA4,5) truncated mutant form does not convert arsenite to monomethylarsonate or dimethylarsinic acid | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
31100 | - |
x * 31100, truncated exon-4 and -5 skipping (DELTA4,5) mutant form, calculated from amino acid sequence | Homo sapiens |
41700 | - |
x * 41700, full-lenth wild type form, calculated from amino acid sequence | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
Ni Sepharose column chromatography, gel filtration | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
A-549 cell | - |
Homo sapiens | - |
HEK-293 cell | - |
Homo sapiens | - |
Hep-G2 cell | - |
Homo sapiens | - |
HL-60 cell | - |
Homo sapiens | - |
K-562 cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + arsenite | - |
Homo sapiens | S-adenosyl-L-homocysteine + monomethylarsonate + dimethylarsinic acid | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 31100, truncated exon-4 and -5 skipping (DELTA4,5) mutant form, calculated from amino acid sequence | Homo sapiens |
? | x * 41700, full-lenth wild type form, calculated from amino acid sequence | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
arsenic (+3 oxidation state) methyltransferase | - |
Homo sapiens |
AS3MT | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | the enzyme plays an important role in the detoxification of arsenicals | Homo sapiens |