Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.1.1.137 extracted from

  • Waters, S.B.; Devesa, V.; Fricke, M.W.; Creed, J.T.; Styblo, M.; Thomas, D.J.
    Glutathione modulates recombinant rat arsenic (+3 oxidation state) methyltransferase-catalyzed formation of trimethylarsine oxide and trimethylarsine (2004), Chem. Res. Toxicol., 17, 1621-1629.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
GSH stimulatory effect on the rate of methylarsonate and dimethylarsinate production from arsenite is concentration-dependent, suppression of formation of trimethylarsine oxide Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
GSH suppression of formation of trimethylarsine oxide, stimulatory effect on the rate of methylarsonate and dimethylarsinate production from arsenite is concentration-dependent Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus Q8VHT6
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + arsenite
-
Rattus norvegicus S-adenosyl-L-homocysteine + methylarsonate
-
?
S-adenosyl-L-methionine + methylarsonite
-
Rattus norvegicus S-adenosyl-L-homocysteine + dimethylarsinate
-
?

Synonyms

Synonyms Comment Organism
arsenic (+3 oxidation state) methyltransferase
-
Rattus norvegicus
AS3MT
-
Rattus norvegicus