Cloned (Comment) | Organism |
---|---|
via RNA isolated from different blood stages | Plasmodium falciparum |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
miltefosine | 50% inhibition at 0.05 mM, 90% inhibition at 0.1 mM | Plasmodium falciparum | |
additional information | not inhibitory: clofibric acid | Plasmodium falciparum | |
phosphocholine | product inhibition, 50% inhibition at 0.05 mM | Plasmodium falciparum | |
S-adenosyl-L-homocysteine | 50% inhibition at 0.05 mM | Plasmodium falciparum |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.079 | - |
Ethanolamine phosphate | pH 8.6, 37°C | Plasmodium falciparum | |
0.153 | - |
S-adenosyl-L-methionine | pH 8.6, 37°C | Plasmodium falciparum |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
31000 | - |
x * 31000, calculated | Plasmodium falciparum |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Plasmodium falciparum | enzyme is involved in biosynthesis of phosphatidylcholine via phosphoethanolamine methylation. Model of pathway | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Plasmodium falciparum | Q6T755 | expression in Escherichia coli | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | enzyme is involved in biosynthesis of phosphatidylcholine via phosphoethanolamine methylation. Model of pathway | Plasmodium falciparum | ? | - |
? | |
S-adenosyl-L-methionine + ethanolamine phosphate | - |
Plasmodium falciparum | S-adenosyl-L-homocysteine + N-methylethanolamine phosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 31000, calculated | Plasmodium falciparum |
More | monopartite enzyme with a single catalytic domain | Plasmodium falciparum |
Synonyms | Comment | Organism |
---|---|---|
Pfpmt | - |
Plasmodium falciparum |
Organism | Comment | pI Value Maximum | pI Value |
---|---|---|---|
Plasmodium falciparum | calculated | - |
5.42 |