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Literature summary for 2.1.1.103 extracted from

  • Pessi, G.; Choi, J.Y.; Reynolds, J.M.; Voelker, D.R.; Mamoun, C.B.
    In vivo evidence for the specificity of Plasmodium falciparum phosphoethanolamine methyltransferase and its coupling to the Kennedy pathway (2005), J. Biol. Chem., 280, 12461-12466.
    View publication on PubMed
Search for more literature for 2.1.1.103

Cloned(Commentary)

Cloned (Comment) Organism
expression in Saccharomyces cerevisiae Plasmodium falciparum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Plasmodium falciparum enzyme is directly coupled to the Kennedy pathway for the de novo synthesis of phosphatidylcholine ?
-
 ?
S-adenosyl-L-methionine + ethanolamine phosphate Plasmodium falciparum the enzyme plays an important role in the biosynthetic pathway of phosphatidylcholine by providing the precursor phosphocholine via a three step S-adenosyl-L-methionine-dependent methylation of phosphoethanolamine. The enzyme function is directly coupled to the Kennedy pathway S-adenosyl-L-homocysteine + N-methylethanolamine phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Plasmodium falciparum
-
-
-
Plasmodium falciparum Q6T755 expression in Saccharomyces cerevisiae
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information enzyme is directly coupled to the Kennedy pathway for the de novo synthesis of phosphatidylcholine Plasmodium falciparum ?
-
 ?
additional information no substrate: phosphatidyl ethanolamine Plasmodium falciparum ?
-
 ?
S-adenosyl-L-methionine + ethanolamine phosphate
-
 Plasmodium falciparum S-adenosyl-L-homocysteine + N-methylethanolamine phosphate
-
 ?
S-adenosyl-L-methionine + ethanolamine phosphate the enzyme plays an important role in the biosynthetic pathway of phosphatidylcholine by providing the precursor phosphocholine via a three step S-adenosyl-L-methionine-dependent methylation of phosphoethanolamine. The enzyme function is directly coupled to the Kennedy pathway Plasmodium falciparum S-adenosyl-L-homocysteine + N-methylethanolamine phosphate
-
 ?

Synonyms

Synonyms Comment Organism
Pfpmt
-
 Plasmodium falciparum