Literature summary for 2.1.1.100 extracted from

Hong, K.M.; Choi, Y.B.; Hong, J.H.; Chang, H.S.; Rhee, K.I.; Park, H.; Paik, M.K.
Cysteine carboxyl O-methylation of human placental 23 kDa protein (1999), Exp. Mol. Med., 31, 30-35.

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Activating Compound

Activating Compound	Comment	Organism	Structure
guanosine 5'-[gamma-thio]-triphosphate	stimulation of 23000 Da protein methylation	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
Mg2+	inhibition of 23000 Da protein methylation	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
S-adenosyl-L-methionine + protein C-terminal S-farnesyl-L-cysteine	methylation of a 23000 Da small G protein is indicated	Homo sapiens	S-adenosyl-L-homocysteine + protein C-terminal S-farnesyl-L-cysteine methyl ester	-	?

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Release 2023.1 (January 2023)