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Literature summary for 2.1.1.1 extracted from
- The relation between nicotinamide N-methyltransferase gene polymorphism and plasma homocysteine concentration in healthy Japanese men (2007), Thromb. Res., 121, 55-58.
Application
| Application | Comment | Organism |
|---|---|---|
| pharmacology | biomarkers for cardiovascular risk factors | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | P40261 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| blood plasma | - |
Homo sapiens | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
association between A/G single nucleotide polymorphism of NNMT gene and total homocysteine concentration in plasma of Japanese man analyzed, genotyping by PCR followed by melting curve analysis, NNMT genotype not determined as a strong determinant of total homocysteine concentration in plasma, modifying effect on plasma homocysteine concentration not excluded | Homo sapiens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| S-adenosyl-L-methionine + nicotinamide | NNMT gene polymorphism as potential marker for cardiovascular risk factors | Homo sapiens | S-adenosyl-L-homocysteine + 1-methylnicotinamide | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| NNMT | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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