Crystallization (Comment) | Organism |
---|---|
- |
Archaeoglobus fulgidus |
the structures of the enzyme in the two-electron reduced state and with sulfite bound to FAD are reported at 1.6 A and 2.5 A resolution, respectively | Archaeoglobus fulgidus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
4Fe-4S cluster | flavoenzyme.The two electrons required for adenylyl sulfate reduction are transferred via two [4Fe-4S] clusters from the surface of the protein to FAD. The large difference in reduction potential of these clusters (-60 mV and -500 mV) can be explained by interactions of the clusters with the protein matrix | Archaeoglobus fulgidus | |
Iron | the two electrons required for the adenylyl sulfate reduction are transferred via two [4Fe-4S] clusters from the surface of the protein to FAD | Archaeoglobus fulgidus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Archaeoglobus fulgidus | - |
- |
- |
Archaeoglobus fulgidus | O28603 | - |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
AMP + sulfite + acceptor = adenylyl sulfate + reduced acceptor | catalysis involves a nucleophilic attack of the N5-atom of reduced FAD on the sulfur atom of the enzyme | Archaeoglobus fulgidus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
adenylyl sulfate + reduced acceptor | - |
Archaeoglobus fulgidus | AMP + sulfite + acceptor | - |
r | |
AMP + sulfite + acceptor | - |
Archaeoglobus fulgidus | adenylyl sulfate + reduced acceptor | - |
r |
Synonyms | Comment | Organism |
---|---|---|
adenosine 5'-phosphosulfate reductase | - |
Archaeoglobus fulgidus |
APS reductase | - |
Archaeoglobus fulgidus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | flavoenzyme.The two electrons required for adenylyl sulfate reduction are transferred via two [4Fe-4S] clusters from the surface of the protein to FAD | Archaeoglobus fulgidus | |
flavin | flavoenzyme | Archaeoglobus fulgidus |