Cloned (Comment) | Organism |
---|---|
the vectors pcDNA3 and pFLAG-CMV2 are used, a leader sequence is cloned into the N-terminus coding region of Srx | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
C99S | catalytic cysteine mutant | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | cytosolic Srx is translocated into the mitochondria under oxidative conditions | Homo sapiens | 5829 | - |
mitochondrion | - |
Homo sapiens | 5739 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + R-SH | Homo sapiens | - |
peroxiredoxin-(S-hydroxycysteine) + ADP + phosphate + R-S-S-R | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
A-549 cell | - |
Homo sapiens | - |
HEK-293 cell | - |
Homo sapiens | - |
HeLa cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + R-SH | - |
Homo sapiens | peroxiredoxin-(S-hydroxycysteine) + ADP + phosphate + R-S-S-R | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Srx | - |
Homo sapiens |
sulfiredoxin | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Homo sapiens |