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Literature summary for 1.8.4.2 extracted from
- Glutathione-insulin transhydrogenase (steer liver) (1971), Methods Enzymol., 17B, 515-519.
No PubMed abstract available
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Cu2+ | - |
Bos taurus |  |
| Hg2+ | - |
Bos taurus | |
| N-acetyl-L-tyrosine ethyl ester | - |
Bos taurus | |
| ribonuclease | - |
Bos taurus |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| additional information | - |
additional information | - |
Bos taurus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
steer | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Bos taurus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Bos taurus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Bos taurus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| GSH + insulin | - |
Bos taurus | GSSG + reduced insulin chain A and B | - |
? | |
| GSH + protein disulfide | prolactin is a poor substrate | Bos taurus | GSSG + protein-dithiol | - |
? | |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 60 | - |
30 min, 30% loss of activity | Bos taurus |
| 80 | - |
30 min, about 60% loss of activity | Bos taurus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.5 | 8.5 | - |
Bos taurus |
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Release 2023.1 (January 2023)
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