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Literature summary for 1.8.4.2 extracted from

  • Schneider, F.; Schauer, R.; Martini, O.; Hahn, J.
    Reversibility of glutathione-insulin-transhydrogenation (protein disulfide-reductase reaction) (1967), Hoppe-Seyler's Z. Physiol. Chem., 348, 391-400.
    View publication on PubMed
Search for more literature for 1.8.4.2

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
150000 200000 gel filtration Bos taurus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Bos taurus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Bos taurus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
6000
-
 purified enzyme Bos taurus

Storage Stability

Storage Stability Organism
-25°C, pH 7.5, phosphate buffer, months without loss of activity Bos taurus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-mercaptoethanol + protein disulfide
-
 Bos taurus 2-mercaptoethanol disulfide + protein-dithiol
-
 ?
cysteamine + protein disulfide
-
 Bos taurus ?
-
 ?
GSH + insulin
-
 Bos taurus GSSG + reduced insulin chain A and B
-
 ?
GSH + protein disulfide
-
 Bos taurus GSSG + protein-dithiol
-
 ?
L-cysteine + protein disulfide
-
 Bos taurus cystine + protein-dithiol
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
-
 Bos taurus

pH Range

pH Minimum pH Maximum Comment Organism
6.5 8.5
-
 Bos taurus