Activating Compound | Comment | Organism | Structure |
---|---|---|---|
carbon tetrachloride | causes marked increases in hepatic TrxR1 activity | Mus musculus | |
Thioacetamide | causes marked increases in hepatic TrxR1 activity | Mus musculus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Na2SeO3 | enhances hepatic TrxR1 activity, but only on the condition that it causes liver injury | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | Q9JMH6 | Kunming mice | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
thioredoxin disulfide + NADPH + H+ | - |
Mus musculus | thioredoxin + NADP+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
thioredoxin reductase 1 | - |
Mus musculus |
TrxR1 | - |
Mus musculus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Mus musculus |