Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | the Grx domain of TXNRD1_v3 localizes first in the emerging protrusion and is then followed into the protrusions by actin and subsequently by tubulin. TXNRD1_v3 can guide actin polymerization in relation to cell membrane restructuring | Homo sapiens | 16020 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q16881 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
A-549 cell | TXNRD1_v3 is induced by estradiol or testosterone treatments | Homo sapiens | - |
HCC-1937 cell | TXNRD1_v3 is induced by estradiol or testosterone treatments | Homo sapiens | - |
heart | transcription of TXNRD1 involves alternative splicing, leading to a number of transcripts also encoding isoforms of TrxR1 that differ from each other at their N-terminal domains. The TXNRD1_v3 isoform contains an atypical N-terminal glutaredoxin domain. Expression of the transcript of this isoform is found predominantly in testis but is also detected in ovary, spleen, heart, liver, kidney, and pancreas | Homo sapiens | - |
HeLa cell | TXNRD1_v3 is induced by estradiol or testosterone treatments | Homo sapiens | - |
kidney | transcription of TXNRD1 involves alternative splicing, leading to a number of transcripts also encoding isoforms of TrxR1 that differ from each other at their N-terminal domains. The TXNRD1_v3 isoform contains an atypical N-terminal glutaredoxin domain. Expression of the transcript of this isoform is found predominantly in testis but is also detected in ovary, spleen, heart, liver, kidney, and pancreas | Homo sapiens | - |
Leydig cell | TXNRD1_v3 is predominantly expressed in the Leydig cells | Homo sapiens | - |
liver | transcription of TXNRD1 involves alternative splicing, leading to a number of transcripts also encoding isoforms of TrxR1 that differ from each other at their N-terminal domains. The TXNRD1_v3 isoform contains an atypical N-terminal glutaredoxin domain. Expression of the transcript of this isoform is found predominantly in testis but is also detected in ovary, spleen, heart, liver, kidney, and pancreas | Homo sapiens | - |
NCI-H157 cell | TXNRD1_v3 is induced by estradiol or testosterone treatments | Homo sapiens | - |
NCI-H23 cell | TXNRD1_v3 is induced by estradiol or testosterone treatments | Homo sapiens | - |
ovary | transcription of TXNRD1 involves alternative splicing, leading to a number of transcripts also encoding isoforms of TrxR1 that differ from each other at their N-terminal domains. The TXNRD1_v3 isoform contains an atypical N-terminal glutaredoxin domain. Expression of the transcript of this isoform is found predominantly in testis but is also detected in ovary, spleen, heart, liver, kidney, and pancreas | Homo sapiens | - |
pancreas | transcription of TXNRD1 involves alternative splicing, leading to a number of transcripts also encoding isoforms of TrxR1 that differ from each other at their N-terminal domains. The TXNRD1_v3 isoform contains an atypical N-terminal glutaredoxin domain. Expression of the transcript of this isoform is found predominantly in testis but is also detected in ovary, spleen, heart, liver, kidney, and pancreas | Homo sapiens | - |
spleen | transcription of TXNRD1 involves alternative splicing, leading to a number of transcripts also encoding isoforms of TrxR1 that differ from each other at their N-terminal domains. The TXNRD1_v3 isoform contains an atypical N-terminal glutaredoxin domain. Expression of the transcript of this isoform is found predominantly in testis but is also detected in ovary, spleen, heart, liver, kidney, and pancreas | Homo sapiens | - |
testis | transcription of TXNRD1 involves alternative splicing, leading to a number of transcripts also encoding isoforms of TrxR1 that differ from each other at their N-terminal domains. The TXNRD1_v3 isoform contains an atypical N-terminal glutaredoxin domain. Expression of the transcript of this isoform is found predominantly in testis but is also detected in ovary, spleen, heart, liver, kidney, and pancreas | Homo sapiens | - |
U-1810 cell | TXNRD1_v3 is induced by estradiol or testosterone treatments | Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
thioredoxin reductase 1 | - |
Homo sapiens |
TrxR1 | - |
Homo sapiens |