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Literature summary for 1.8.1.9 extracted from
- Involvement of thioredoxin reductase 1 in the regulation of redox balance and viability of rheumatoid synovial cells (2008), Biochem. Biophys. Res. Commun., 367, 491-496.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Homo sapiens | function of TRXR1 in the self-defense mechanism against self-generated oxidative stress | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | Q16881 | patients with rheumatoid arthritis | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| synovial cell | thioredoxin reductase 1 is upregulated in synovial cell from patients with rheumatoid arthritis. TRXR1 suppresses hydrogen peroxide and inhibits apoptosis of rheumatoid arthritis synovial cells | Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | function of TRXR1 in the self-defense mechanism against self-generated oxidative stress | Homo sapiens | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| thioredoxin reductase 1 | - |
Homo sapiens |
| TrxR1 | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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