Inhibitors | Comment | Organism | Structure |
---|---|---|---|
4-hydroxy-2-nonenal | 0.005-0.025 mM, IC50: 0.0038 mM, irreversible inhibition; 0.05 mM, remarkable lost inhibition | Rattus norvegicus | |
curcumin | IC50: 0.0036 mM | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
5,5'-dithiobis(2-nitrobenzoic acid) + NADPH | - |
Rattus norvegicus | 2-nitro-5-thiobenzoate + NADP | - |
? | |
thioredoxin + NADP+ | - |
Rattus norvegicus | thioredoxin disulfide + NADPH | - |
? |
Synonyms | Comment | Organism |
---|---|---|
thioredoxin reductase | - |
Rattus norvegicus |
TrxR | - |
Rattus norvegicus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0036 | - |
IC50: 0.0036 mM | Rattus norvegicus | curcumin | |
0.0038 | - |
0.005-0.025 mM, IC50: 0.0038 mM, irreversible inhibition | Rattus norvegicus | 4-hydroxy-2-nonenal |