Organism | UniProt | Comment | Textmining |
---|---|---|---|
Candida albicans | Q59NQ5 | - |
- |
Source Tissue | Comment | Organism | Textmining |
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General Information | Comment | Organism |
---|---|---|
physiological function | a GLR1-deficient strain is not viable. During filamentation, nongrowing hyphal GLR1-overexpressing cells exhibit resistance against oxidants and cellular methylglyoxal is significantly decreased, which concomitantly increases expression of genes encoding energy-generating enzymes, including fructose-1,6-bisphosphate aldolase, glyceraldehyde-3-phosphate dehydrogenase, and alcohol dehydrogenase (ADH1), with remarkable repression of Efg1-signaling cascades | Candida albicans |