Cloned (Comment) | Organism |
---|---|
expressed in NIH-3T3, TM-3, MSC-1, and TM-4 cells | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
GSSG + NADPH + H+ | - |
Mus musculus | GSH + NADP+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
TGR | - |
Mus musculus |
thioredoxin glutathione reductase | - |
Mus musculus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | - |
Mus musculus | |
NADPH | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
physiological function | thioredoxin glutathione reductase binding to retinoic acid receptor is required for the retinoic acid-dependent retinoic acid receptor association with chromatin, retinoic acid receptor activity damaged by oxidative stress is restored by thioredoxin glutathione reductase | Mus musculus |