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Literature summary for 1.8.1.7 extracted from
- Glutathione reductase (1985), Methods Enzymol., 113, 484-490.
General Stability
| General Stability | Organism |
|---|---|
| freezing denaturates | Rattus norvegicus |
| freezing denaturates | Bos taurus |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.008 | - |
NADPH | - |
Rattus norvegicus |  |
| 0.021 | - |
NADPH | - |
Bos taurus | |
| 0.0263 | - |
GSSG | - |
Rattus norvegicus | |
| 0.101 | - |
GSSG | - |
Bos taurus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytoplasm | - |
Rattus norvegicus | 5737 | - |
| cytoplasm | - |
Bos taurus | 5737 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 100000 | - |
- |
Bos taurus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| GSSG + NADPH | Rattus norvegicus | serves in detoxification | glutathione + NADP+ | - |
ir | |
| GSSG + NADPH | Bos taurus | serves in detoxification | glutathione + NADP+ | - |
ir | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
| Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Rattus norvegicus |
- |
Bos taurus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
| liver | - |
Bos taurus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
assay methods | Rattus norvegicus |
| additional information | - |
assay methods | Bos taurus |
| 204 | - |
- |
Rattus norvegicus |
| 204 | - |
- |
Bos taurus |
| 269 | - |
- |
Rattus norvegicus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| GSSG + NADPH | - |
Rattus norvegicus | glutathione + NADP+ | - |
ir | |
| GSSG + NADPH | - |
Bos taurus | glutathione + NADP+ | - |
ir | |
| GSSG + NADPH | serves in detoxification | Rattus norvegicus | glutathione + NADP+ | - |
ir | |
| GSSG + NADPH | serves in detoxification | Bos taurus | glutathione + NADP+ | - |
ir | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | - |
Rattus norvegicus |
| dimer | - |
Bos taurus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7 | - |
- |
Rattus norvegicus |
| 7 | - |
- |
Bos taurus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| FAD | 2 mol of FAD per mol of enzyme | Rattus norvegicus | |
| FAD | 2 mol of FAD per mol of enzyme | Bos taurus | |
| FAD | FAD enzyme | Rattus norvegicus | |
| FAD | FAD enzyme | Bos taurus | |
| flavin | flavoprotein | Rattus norvegicus | |
| flavin | flavoprotein | Bos taurus | |
| NADPH | - |
Rattus norvegicus | |
| NADPH | - |
Bos taurus | |
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Release 2023.1 (January 2023)
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