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Literature summary for 1.8.1.6 extracted from

  • Maresca, B.; Jacobson, E.; Medoff, G.; Kobayashi, G.
    Cystine reductase in the dimorphic fungus Histoplasma capsulatum (1978), J. Bacteriol., 135, 987-992.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.8.1.6

Inhibitors

Inhibitors Comment Organism Structure
p-chloromercuriphenylsulfonic acid strong Histoplasma capsulatum

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.11
-
 L-cystine
-
 Histoplasma capsulatum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
NADH + L-cystine Histoplasma capsulatum the enzyme may provide reduced sulfhydryl groups involved in the transition of mycelium to yeast form ?
-
 ?

Organism

Organism UniProt Comment Textmining
Histoplasma capsulatum
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
additional information the enzyme is phase specific it is not present in mycelium appears early in the transition of mycelium to yeast Histoplasma capsulatum
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
NADH + L-cystine
-
 Histoplasma capsulatum NAD+ + L-cysteine
-
 ?
NADH + L-cystine the enzyme may provide reduced sulfhydryl groups involved in the transition of mycelium to yeast form Histoplasma capsulatum ?
-
 ?

Cofactor

Cofactor Comment Organism Structure
NADH
-
 Histoplasma capsulatum