Literature summary for 1.8.1.4 extracted from

Danson, M.J.; McQuattie, A.; Stevenson, K.J.
Dihydrolipoamide dehydrogenase from halophilic archaebacteria: purification and properties of the enzyme from Halobacterium halobium (1986), Biochemistry, 25, 3880-3884.

No PubMed abstract available

Search for more literature for 1.8.1.4

Inhibitors

Inhibitors	Comment	Organism	Structure
p-Aminophenyldichloroarsine	-	Halobacterium salinarum

Metals/Ions

Metals/Ions	Comment	Organism	Structure
NaCl	completely inactive in absence of NaCl	Halobacterium salinarum

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
58000	-	2 * 58000, SDS-PAGE	Halobacterium salinarum

Organism

Organism	UniProt	Comment	Textmining
Halobacterium salinarum	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Halobacterium salinarum

Reaction

Reaction	Comment	Organism	Reaction ID
protein N6-(dihydrolipoyl)lysine + NAD+ = protein N6-(lipoyl)lysine + NADH + H+	involvement of a reversibly reducible disulfide bond in catalytic mechanism	Halobacterium salinarum	a

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
35	-	-	Halobacterium salinarum

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
dihydrolipoamide + NAD+	-	Halobacterium salinarum	lipoamide + NADH	-	?

Subunits

Subunits	Comment	Organism
dimer	2 * 58000, SDS-PAGE	Halobacterium salinarum

Cofactor

Cofactor	Comment	Organism	Structure
flavin	-	Halobacterium salinarum
NAD+	-	Halobacterium salinarum

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Release 2023.1 (January 2023)