Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
49690 | - |
x * 49690, calculation from nucleotide sequence | Sus scrofa |
51274 | - |
x * 51274, calculation from nucleotide sequence | Escherichia coli |
54000 | - |
x * 54000, SDS-PAGE | Geobacillus stearothermophilus |
54000 | - |
x * 54000, SDS-PAGE | Ascaris suum |
55000 | - |
x * 55000, SDS-PAGE | Bos taurus |
56000 | - |
x * 56000, SDS-PAGE | Rattus norvegicus |
56000 | - |
x * 56000, SDS-PAGE | Azotobacter vinelandii |
56000 | - |
x * 56000, enzyme from liver enzyme | Rattus norvegicus |
58000 | - |
x * 58000, SDS-PAGE | Halobacterium salinarum |
58000 | - |
x * 58000, enzyme from heart, SDS-PAGE | Rattus norvegicus |
59000 | - |
x * 59000, SDS-PAGE | Pisum sativum |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Saccharomyces pastorianus | the enzyme is a component of the three 2-oxoacid dehydrogenase complexes oxidizing pyruvate, 2-oxoglutarate, and the branched-chain 2-oxo acids | ? | - |
? | |
additional information | Bacillus subtilis | the enzyme is a component of the three 2-oxoacid dehydrogenase complexes oxidizing pyruvate, 2-oxoglutarate, and the branched-chain 2-oxo acids | ? | - |
? | |
additional information | Escherichia coli | the enzyme is a component of the three 2-oxoacid dehydrogenase complexes oxidizing pyruvate, 2-oxoglutarate, and the branched-chain 2-oxo acids | ? | - |
? | |
additional information | Homo sapiens | the enzyme is a component of the three 2-oxoacid dehydrogenase complexes oxidizing pyruvate, 2-oxoglutarate, and the branched-chain 2-oxo acids | ? | - |
? | |
additional information | Rattus norvegicus | the enzyme is a component of the three 2-oxoacid dehydrogenase complexes oxidizing pyruvate, 2-oxoglutarate, and the branched-chain 2-oxo acids | ? | - |
? | |
additional information | Sus scrofa | the enzyme is a component of the three 2-oxoacid dehydrogenase complexes oxidizing pyruvate, 2-oxoglutarate, and the branched-chain 2-oxo acids | ? | - |
? | |
additional information | Saccharomyces cerevisiae | the enzyme is a component of the three 2-oxoacid dehydrogenase complexes oxidizing pyruvate, 2-oxoglutarate, and the branched-chain 2-oxo acids | ? | - |
? | |
additional information | Bos taurus | the enzyme is a component of the three 2-oxoacid dehydrogenase complexes oxidizing pyruvate, 2-oxoglutarate, and the branched-chain 2-oxo acids | ? | - |
? | |
additional information | Geobacillus stearothermophilus | the enzyme is a component of the three 2-oxoacid dehydrogenase complexes oxidizing pyruvate, 2-oxoglutarate, and the branched-chain 2-oxo acids | ? | - |
? | |
additional information | Pisum sativum | the enzyme is a component of the three 2-oxoacid dehydrogenase complexes oxidizing pyruvate, 2-oxoglutarate, and the branched-chain 2-oxo acids | ? | - |
? | |
additional information | Pseudomonas aeruginosa | the enzyme is a component of the three 2-oxoacid dehydrogenase complexes oxidizing pyruvate, 2-oxoglutarate, and the branched-chain 2-oxo acids | ? | - |
? | |
additional information | Pseudomonas putida | the enzyme is a component of the three 2-oxoacid dehydrogenase complexes oxidizing pyruvate, 2-oxoglutarate, and the branched-chain 2-oxo acids | ? | - |
? | |
additional information | Halobacterium salinarum | the enzyme is a component of the three 2-oxoacid dehydrogenase complexes oxidizing pyruvate, 2-oxoglutarate, and the branched-chain 2-oxo acids | ? | - |
? | |
additional information | Ascaris suum | the enzyme is a component of the three 2-oxoacid dehydrogenase complexes oxidizing pyruvate, 2-oxoglutarate, and the branched-chain 2-oxo acids | ? | - |
? | |
additional information | Azotobacter vinelandii | the enzyme is a component of the three 2-oxoacid dehydrogenase complexes oxidizing pyruvate, 2-oxoglutarate, and the branched-chain 2-oxo acids | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Ascaris suum | - |
dihydrolipoamide dehydrogenase E3 | - |
Azotobacter vinelandii | - |
dihydrolipoamide dehydrogenase E3 | - |
Bacillus subtilis | - |
dihydrolipoamide dehydrogenase E3 | - |
Bos taurus | - |
- |
- |
Escherichia coli | - |
K-12 | - |
Escherichia coli | - |
dihydrolipoamide dehydrogenase E3 | - |
Geobacillus stearothermophilus | - |
dihydrolipoamide dehydrogenase E3 | - |
Halobacterium salinarum | - |
dihydrolipoamide dehydrogenase E3 | - |
Homo sapiens | - |
- |
- |
Pisum sativum | - |
dihydrolipoamide dehydrogenase E3 | - |
Pseudomonas aeruginosa | - |
dihydrolipoamide dehydrogenase E3 | - |
Pseudomonas putida | - |
dihydrolipoamide dehydrogenase E3 | - |
Rattus norvegicus | - |
dihydrolipoamide dehydrogenase E3 | - |
Saccharomyces cerevisiae | - |
dihydrolipoamide dehydrogenase E3 | - |
Saccharomyces pastorianus | - |
dihydrolipoamide dehydrogenase E3 | - |
Sus scrofa | - |
dihydrolipoamide dehydrogenase E3 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Rattus norvegicus | - |
brain | - |
Sus scrofa | - |
heart | - |
Sus scrofa | - |
heart | - |
Bos taurus | - |
kidney | - |
Bos taurus | - |
leaf | - |
Pisum sativum | - |
liver | - |
Homo sapiens | - |
liver | - |
Rattus norvegicus | - |
muscle | - |
Ascaris suum | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
dihydrolipoamide + NAD+ | - |
Saccharomyces pastorianus | lipoamide + NADH | - |
? | |
dihydrolipoamide + NAD+ | - |
Bacillus subtilis | lipoamide + NADH | - |
? | |
dihydrolipoamide + NAD+ | - |
Escherichia coli | lipoamide + NADH | - |
? | |
dihydrolipoamide + NAD+ | - |
Homo sapiens | lipoamide + NADH | - |
? | |
dihydrolipoamide + NAD+ | - |
Rattus norvegicus | lipoamide + NADH | - |
? | |
dihydrolipoamide + NAD+ | - |
Sus scrofa | lipoamide + NADH | - |
? | |
dihydrolipoamide + NAD+ | - |
Saccharomyces cerevisiae | lipoamide + NADH | - |
? | |
dihydrolipoamide + NAD+ | - |
Bos taurus | lipoamide + NADH | - |
? | |
dihydrolipoamide + NAD+ | - |
Geobacillus stearothermophilus | lipoamide + NADH | - |
? | |
dihydrolipoamide + NAD+ | - |
Pisum sativum | lipoamide + NADH | - |
? | |
dihydrolipoamide + NAD+ | - |
Pseudomonas aeruginosa | lipoamide + NADH | - |
? | |
dihydrolipoamide + NAD+ | - |
Pseudomonas putida | lipoamide + NADH | - |
? | |
dihydrolipoamide + NAD+ | - |
Halobacterium salinarum | lipoamide + NADH | - |
? | |
dihydrolipoamide + NAD+ | - |
Ascaris suum | lipoamide + NADH | - |
? | |
dihydrolipoamide + NAD+ | - |
Azotobacter vinelandii | lipoamide + NADH | - |
? | |
additional information | the enzyme is a component of the three 2-oxoacid dehydrogenase complexes oxidizing pyruvate, 2-oxoglutarate, and the branched-chain 2-oxo acids | Saccharomyces pastorianus | ? | - |
? | |
additional information | the enzyme is a component of the three 2-oxoacid dehydrogenase complexes oxidizing pyruvate, 2-oxoglutarate, and the branched-chain 2-oxo acids | Bacillus subtilis | ? | - |
? | |
additional information | the enzyme is a component of the three 2-oxoacid dehydrogenase complexes oxidizing pyruvate, 2-oxoglutarate, and the branched-chain 2-oxo acids | Escherichia coli | ? | - |
? | |
additional information | the enzyme is a component of the three 2-oxoacid dehydrogenase complexes oxidizing pyruvate, 2-oxoglutarate, and the branched-chain 2-oxo acids | Homo sapiens | ? | - |
? | |
additional information | the enzyme is a component of the three 2-oxoacid dehydrogenase complexes oxidizing pyruvate, 2-oxoglutarate, and the branched-chain 2-oxo acids | Rattus norvegicus | ? | - |
? | |
additional information | the enzyme is a component of the three 2-oxoacid dehydrogenase complexes oxidizing pyruvate, 2-oxoglutarate, and the branched-chain 2-oxo acids | Sus scrofa | ? | - |
? | |
additional information | the enzyme is a component of the three 2-oxoacid dehydrogenase complexes oxidizing pyruvate, 2-oxoglutarate, and the branched-chain 2-oxo acids | Saccharomyces cerevisiae | ? | - |
? | |
additional information | the enzyme is a component of the three 2-oxoacid dehydrogenase complexes oxidizing pyruvate, 2-oxoglutarate, and the branched-chain 2-oxo acids | Bos taurus | ? | - |
? | |
additional information | the enzyme is a component of the three 2-oxoacid dehydrogenase complexes oxidizing pyruvate, 2-oxoglutarate, and the branched-chain 2-oxo acids | Geobacillus stearothermophilus | ? | - |
? | |
additional information | the enzyme is a component of the three 2-oxoacid dehydrogenase complexes oxidizing pyruvate, 2-oxoglutarate, and the branched-chain 2-oxo acids | Pisum sativum | ? | - |
? | |
additional information | the enzyme is a component of the three 2-oxoacid dehydrogenase complexes oxidizing pyruvate, 2-oxoglutarate, and the branched-chain 2-oxo acids | Pseudomonas aeruginosa | ? | - |
? | |
additional information | the enzyme is a component of the three 2-oxoacid dehydrogenase complexes oxidizing pyruvate, 2-oxoglutarate, and the branched-chain 2-oxo acids | Pseudomonas putida | ? | - |
? | |
additional information | the enzyme is a component of the three 2-oxoacid dehydrogenase complexes oxidizing pyruvate, 2-oxoglutarate, and the branched-chain 2-oxo acids | Halobacterium salinarum | ? | - |
? | |
additional information | the enzyme is a component of the three 2-oxoacid dehydrogenase complexes oxidizing pyruvate, 2-oxoglutarate, and the branched-chain 2-oxo acids | Ascaris suum | ? | - |
? | |
additional information | the enzyme is a component of the three 2-oxoacid dehydrogenase complexes oxidizing pyruvate, 2-oxoglutarate, and the branched-chain 2-oxo acids | Azotobacter vinelandii | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | - |
Saccharomyces pastorianus |
? | - |
Homo sapiens |
? | x * 54000, SDS-PAGE | Geobacillus stearothermophilus |
? | x * 54000, SDS-PAGE | Ascaris suum |
? | x * 56000, SDS-PAGE | Rattus norvegicus |
? | x * 56000, SDS-PAGE | Azotobacter vinelandii |
? | x * 55000, SDS-PAGE | Bos taurus |
? | x * 58000, SDS-PAGE | Halobacterium salinarum |
? | x * 59000, SDS-PAGE | Pisum sativum |
? | x * 58000, enzyme from heart, SDS-PAGE | Rattus norvegicus |
? | x * 56000, enzyme from liver enzyme | Rattus norvegicus |
? | x * 49690, calculation from nucleotide sequence | Sus scrofa |
? | x * 51274, calculation from nucleotide sequence | Escherichia coli |
Synonyms | Comment | Organism |
---|---|---|
dihydrolipoamide dehydrogenase E3 | common component of the three 2-oxoacid dehydrogenase complexes oxidizing pyruvate, 2-oxoglutarate, and the branched-chain 2-oxo acids | Saccharomyces pastorianus |
dihydrolipoamide dehydrogenase E3 | common component of the three 2-oxoacid dehydrogenase complexes oxidizing pyruvate, 2-oxoglutarate, and the branched-chain 2-oxo acids | Bacillus subtilis |
dihydrolipoamide dehydrogenase E3 | common component of the three 2-oxoacid dehydrogenase complexes oxidizing pyruvate, 2-oxoglutarate, and the branched-chain 2-oxo acids | Escherichia coli |
dihydrolipoamide dehydrogenase E3 | common component of the three 2-oxoacid dehydrogenase complexes oxidizing pyruvate, 2-oxoglutarate, and the branched-chain 2-oxo acids | Homo sapiens |
dihydrolipoamide dehydrogenase E3 | common component of the three 2-oxoacid dehydrogenase complexes oxidizing pyruvate, 2-oxoglutarate, and the branched-chain 2-oxo acids | Rattus norvegicus |
dihydrolipoamide dehydrogenase E3 | common component of the three 2-oxoacid dehydrogenase complexes oxidizing pyruvate, 2-oxoglutarate, and the branched-chain 2-oxo acids | Sus scrofa |
dihydrolipoamide dehydrogenase E3 | common component of the three 2-oxoacid dehydrogenase complexes oxidizing pyruvate, 2-oxoglutarate, and the branched-chain 2-oxo acids | Saccharomyces cerevisiae |
dihydrolipoamide dehydrogenase E3 | common component of the three 2-oxoacid dehydrogenase complexes oxidizing pyruvate, 2-oxoglutarate, and the branched-chain 2-oxo acids | Bos taurus |
dihydrolipoamide dehydrogenase E3 | common component of the three 2-oxoacid dehydrogenase complexes oxidizing pyruvate, 2-oxoglutarate, and the branched-chain 2-oxo acids | Geobacillus stearothermophilus |
dihydrolipoamide dehydrogenase E3 | common component of the three 2-oxoacid dehydrogenase complexes oxidizing pyruvate, 2-oxoglutarate, and the branched-chain 2-oxo acids | Pisum sativum |
dihydrolipoamide dehydrogenase E3 | common component of the three 2-oxoacid dehydrogenase complexes oxidizing pyruvate, 2-oxoglutarate, and the branched-chain 2-oxo acids | Pseudomonas aeruginosa |
dihydrolipoamide dehydrogenase E3 | common component of the three 2-oxoacid dehydrogenase complexes oxidizing pyruvate, 2-oxoglutarate, and the branched-chain 2-oxo acids | Pseudomonas putida |
dihydrolipoamide dehydrogenase E3 | common component of the three 2-oxoacid dehydrogenase complexes oxidizing pyruvate, 2-oxoglutarate, and the branched-chain 2-oxo acids | Halobacterium salinarum |
dihydrolipoamide dehydrogenase E3 | common component of the three 2-oxoacid dehydrogenase complexes oxidizing pyruvate, 2-oxoglutarate, and the branched-chain 2-oxo acids | Ascaris suum |
dihydrolipoamide dehydrogenase E3 | common component of the three 2-oxoacid dehydrogenase complexes oxidizing pyruvate, 2-oxoglutarate, and the branched-chain 2-oxo acids | Azotobacter vinelandii |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Saccharomyces pastorianus | |
NAD+ | - |
Bacillus subtilis | |
NAD+ | - |
Escherichia coli | |
NAD+ | - |
Homo sapiens | |
NAD+ | - |
Rattus norvegicus | |
NAD+ | - |
Sus scrofa | |
NAD+ | - |
Saccharomyces cerevisiae | |
NAD+ | - |
Bos taurus | |
NAD+ | - |
Geobacillus stearothermophilus | |
NAD+ | - |
Pisum sativum | |
NAD+ | - |
Pseudomonas aeruginosa | |
NAD+ | - |
Pseudomonas putida | |
NAD+ | - |
Halobacterium salinarum | |
NAD+ | - |
Ascaris suum | |
NAD+ | - |
Azotobacter vinelandii |