Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | activity is dependent on a redox-active cysteine at the active centre | Trypanosoma cruzi |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(4'-chloro-2,2':6',2''-terpyridine)platinum(II) ammine complex | irreversible, altering specifically the Cys52 residue in the active center, increased oxidase activity | Trypanosoma cruzi | |
(4-picoline) (4'-p-bromophenyl-2,2':6',2''-terpyridine)platinum(II) complex | irreversible, altering specifically the Cys52 residue in the active center, increased oxidase activity | Trypanosoma cruzi |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Trypanosoma cruzi | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
trypanothione disulfide + NADPH | - |
Trypanosoma cruzi | trypanothione + NADP+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
TR | - |
Trypanosoma cruzi |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | - |
Trypanosoma cruzi | |
NADPH | - |
Trypanosoma cruzi |