Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
CoA-glutathione + NADPH | Escherichia coli | metabolism of CoA-glutathione disulfide, role may be to replenish the CoA pool from CoAS-SG formed either chemically or enzymatically during cell growth, accumulation of CoAS-SG in vivo in spite of high enzyme levels indicates involvement of a control mechanism | glutathione + CoA + NADP+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
specific activity of enzyme in crude extract increases during growth from early log phase into stationary phase and during a shift from aerobic to anaerobic growth | Escherichia coli |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
CoA-glutathione + NADPH | substrate coenzyme A-glutathione mixed disulfide, CoAS-SG, is capable of binding one molecule of Fe3+ | Escherichia coli | glutathione + CoA + NADP+ | - |
ir | |
CoA-glutathione + NADPH | metabolism of CoA-glutathione disulfide, role may be to replenish the CoA pool from CoAS-SG formed either chemically or enzymatically during cell growth, accumulation of CoAS-SG in vivo in spite of high enzyme levels indicates involvement of a control mechanism | Escherichia coli | glutathione + CoA + NADP+ | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | NADPH-dependent | Escherichia coli |