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Literature summary for 1.7.5.1 extracted from

  • Rothery, R.A.; Bertero, M.G.; Spreter, T.; Bouromand, N.; Strynadka, N.C.; Weiner, J.H.
    Protein crystallography reveals a role for the FS0 cluster of Escherichia coli nitrate reductase A (NarGHI) in enzyme maturation (2010), J. Biol. Chem., 285, 8801-8807.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.7.5.1

Crystallization (Commentary)

Crystallization (Comment) Organism
-
 Escherichia coli

Protein Variants

Protein Variants Comment Organism
H49C the mutant lacks catalytic activity Escherichia coli
H49S the mutant lacks catalytic activity and the FS0 [4Fe-4S] cluster and molybdo-bis(pyranopterin guanine dinucleotide) cofactor but retains the GDP moieties Escherichia coli
R94S the mutant shows a concomitant decrease in enzyme turnover to about 30% of the wild type Escherichia coli

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Escherichia coli 16020
-

Organism

Organism UniProt Comment Textmining
Escherichia coli P09152
-
-
Escherichia coli LCB79 P09152
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
nitrate + 2-hydroxy-3-(3-methyl-2-butenyl)-1,4-naphthoquinol
-
 Escherichia coli nitrite + 2-hydroxy-3-(3-methyl-2-butenyl)-1,4-naphthoquinone + H2O
-
 ?
nitrate + 2-hydroxy-3-(3-methyl-2-butenyl)-1,4-naphthoquinol
-
 Escherichia coli LCB79 nitrite + 2-hydroxy-3-(3-methyl-2-butenyl)-1,4-naphthoquinone + H2O
-
 ?
nitrate + reduced benzyl viologen
-
 Escherichia coli nitrite + benzyl viologen
-
 ?
nitrate + reduced benzyl viologen
-
 Escherichia coli LCB79 nitrite + benzyl viologen
-
 ?

Synonyms

Synonyms Comment Organism
NarG catalytic subunit of NarGHI Escherichia coli
NarGHI
-
 Escherichia coli
nitrate reductase A
-
 Escherichia coli
quinol:nitrate oxidoreductase
-
 Escherichia coli

Cofactor

Cofactor Comment Organism Structure
4Fe-4S-center
-
 Escherichia coli
heme
-
 Escherichia coli
molybdo-bis(pyranopterin guanine dinucleotide)
-
 Escherichia coli