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Literature summary for 1.7.3.3 extracted from
- Uricase, subunit composition and resistance to denaturants (1974), Biochemistry, 13, 888-892.
General Stability
| General Stability | Organism |
|---|---|
| unusually resistant to guanidinium chloride | Sus scrofa |
| unusually resistant to SDS | Sus scrofa |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| copper | copper : uricase ratio is 1 : 1 | Sus scrofa |  |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 32000 | - |
alpha4, 4 * 32000, SDS-PAGE | Sus scrofa |
| 125000 | - |
short-column meniscus depletion sedimentation equilibrium | Sus scrofa |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| urate + O2 + H2O | Sus scrofa | - |
5-hydroxyisourate + H2O2 | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Sus scrofa | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Sus scrofa | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| urate + O2 + H2O | - |
Sus scrofa | 5-hydroxyisourate + H2O2 | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| tetramer | alpha4, 4 * 32000, SDS-PAGE | Sus scrofa |
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