Application | Comment | Organism |
---|---|---|
medicine | potential target for the treatment of leukemia | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
transfection of HL-60 leukemia cells, expressed in COS-7 cells as His-tag fusion protein | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
37800 | - |
calculated from the deduced amino acid sequence | Homo sapiens |
40000 | - |
His-tag fusion protein, SDS-PAGE | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
NADPH + guanosine 5'-phosphate | Homo sapiens | important for the maintenance of the intracellular adenine guanine balance, possible role in the regulation of differentiation of leukemia cells | NADP+ + inosine 5'-phosphate + NH3 | - |
ir |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q9P2T1 | - |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
no glycoprotein | no glycosylation site found | Homo sapiens |
Purification (Comment) | Organism |
---|---|
from recombinant COS-7 cells | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
A-549 cell | - |
Homo sapiens | - |
G-361 cell | - |
Homo sapiens | - |
heart | - |
Homo sapiens | - |
HeLa-S3 cell | - |
Homo sapiens | - |
HL-60 cell | - |
Homo sapiens | - |
K-562 cell | - |
Homo sapiens | - |
kidney | - |
Homo sapiens | - |
liver | - |
Homo sapiens | - |
lung | - |
Homo sapiens | - |
MOLT-4 cell | - |
Homo sapiens | - |
monocyte | peripheral | Homo sapiens | - |
ovary | - |
Homo sapiens | - |
pancreas | - |
Homo sapiens | - |
placenta | - |
Homo sapiens | - |
prostate | - |
Homo sapiens | - |
RAJI cell | - |
Homo sapiens | - |
skeletal muscle | - |
Homo sapiens | - |
small intestine | - |
Homo sapiens | - |
spleen | - |
Homo sapiens | - |
SW-480 cell | - |
Homo sapiens | - |
testis | - |
Homo sapiens | - |
thymus | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
NADPH + guanosine 5'-phosphate | - |
Homo sapiens | NADP+ + inosine 5'-phosphate + NH3 | - |
ir | |
NADPH + guanosine 5'-phosphate | important for the maintenance of the intracellular adenine guanine balance, possible role in the regulation of differentiation of leukemia cells | Homo sapiens | NADP+ + inosine 5'-phosphate + NH3 | - |
ir |
Synonyms | Comment | Organism |
---|---|---|
GMPR2 | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Homo sapiens |