Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.7.1.14 extracted from

  • Kramos, B.; Menyhard, D.K.; Olah, J.
    Direct hydride shift mechanism and stereoselectivity of P450nor confirmed by QM/MM calculations (2012), J. Phys. Chem. B, 116, 872-885.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Fusarium oxysporum P23295
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information quantum chemical and combined quantum mechanics/molecular mechanics clearly favor a direct hydride transfer taking place between the NADH cofactor and NO, where the hydride is shifted to the N of NO. The barriers obtained for the syn, Pro-R conformation of NADH are lower and show significantly less variation than the barriers obtained in the case of anti conformation Fusarium oxysporum ?
-
?

Synonyms

Synonyms Comment Organism
CYP55A1
-
Fusarium oxysporum
P450nor
-
Fusarium oxysporum