Activating Compound | Comment | Organism | Structure |
---|---|---|---|
butylated hydroxyanisole | inducer | Rattus norvegicus | |
oltipraz | inducer | Rattus norvegicus |
Application | Comment | Organism |
---|---|---|
medicine | strain difference where Sprague Dawley rats possess a sex-dependent expression and activity of Nqo1 and August Copenhagen x Irish rats exhibit no sexual dimorphism may provide an important tool when using these rat models for oxidative stress and cancer studies | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Rattus norvegicus | 5829 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
32000 | - |
Western blot analysis | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
Sprague Dawley and August Copenhagen x Irish strains | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | in the Sprague Dawley strain, gender dimorphic expression of Nqo1 with female mRNA, protein, and activity levels being significantly higher than in males. Minimal differences in Nqo1 mRNA, protein, and activity levels between August Copenhagen x Irish males and females | Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
NADPH + H+ + oxidized 2,6-dichlorophenolindophenol | - |
Rattus norvegicus | NADP+ + reduced 2,6-dichlorophenolindophenol | - |
? |
Synonyms | Comment | Organism |
---|---|---|
NAD(P)H:quinone oxidoreducatase 1 | - |
Rattus norvegicus |
NQO1 | - |
Rattus norvegicus |