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Literature summary for 1.6.5.10 extracted from

  • Crosas, E.; Porte, S.; Moeini, A.; Farres, J.; Biosca, J.A.; Pares, X.; Fernandez, M.R.
    Novel alkenal/one reductase activity of yeast NADPH:quinone reductase Zta1p. Prospect of the functional role for the zeta-crystallin family (2011), Chem. Biol. Interact., 191, 32-37.
    View publication on PubMed
Search for more literature for 1.6.5.10

Crystallization (Commentary)

Crystallization (Comment) Organism
-
 Saccharomyces cerevisiae

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.004
-
 9,10-phenanthrenequinone pH 7.0, temperature not specified in the publication Saccharomyces cerevisiae
0.009
-
 1,2-naphthoquinone pH 7.0, temperature not specified in the publication Saccharomyces cerevisiae

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1,2-naphthoquinone + NADPH + H+
-
 Saccharomyces cerevisiae 1,2-naphthoquinol + NADP+
-
 ?
9,10-phenanthrenequinone + NADPH + H+
-
 Saccharomyces cerevisiae 9,10-phenanthrenequinol + NADP+
-
 ?
additional information trace activity with substrates acrolein, cinnamaldehyde, 3-buten-2-one, 3-penten-2-one, 3-nonen-2-one Saccharomyces cerevisiae ?
-
 ?

Synonyms

Synonyms Comment Organism
Zta1p
-
 Saccharomyces cerevisiae

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
4.2
-
 9,10-phenanthrenequinone pH 7.0, temperature not specified in the publication Saccharomyces cerevisiae
4.2
-
 1,2-naphthoquinone pH 7.0, temperature not specified in the publication Saccharomyces cerevisiae

Expression

Organism Comment Expression
Saccharomyces cerevisiae induction under different types of cellular stress, including ethanol and dimethylsulfoxide exposure and by reaching the stationary growth phase up

General Information

General Information Comment Organism
physiological function presence of Zta1p has an in vivo protective effect on yeast strains exposed to the toxic substrate 3-penten-2-one Saccharomyces cerevisiae

kcat/KM [mM/s]

kcat/KM Value [1/mMs-1] kcat/KM Value Maximum [1/mMs-1] Substrate Comment Organism Structure
462
-
 1,2-naphthoquinone pH 7.0, temperature not specified in the publication Saccharomyces cerevisiae
1041
-
 9,10-phenanthrenequinone pH 7.0, temperature not specified in the publication Saccharomyces cerevisiae