Activating Compound | Comment | Organism | Structure |
---|---|---|---|
doxorubicin | induction of superoxide production by doxorubicin is much higher in hearts of wild-type mice than in subunit gp91phox knock-out mice | Mus musculus | |
additional information | superoxide production is induced by addition of NADPH cytochrome P450 reductase | Mus musculus |
Application | Comment | Organism |
---|---|---|
medicine | induction of superoxide production by doxorubicin is much higher in hearts of wild-type mice than in subunit gp91phox knock-out mice. Superoxide production is similarly induced by addition of NADPH cytochrome P450 reductase | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
female wild-type and NAD(P)H oxidase deficient gp91phox knock-out mice | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
heart | induction of superoxide production by doxorubicin is much higher in hearts of wild-type mice than in subunit gp91phox knock-out mice. Superoxide production is similarly induced by addition of NADPH cytochrome P450 reductase | Mus musculus | - |