Cloned (Comment) | Organism |
---|---|
expression in COS-7 cell | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
phagosome | after Fcgamma receptor-induced phagocytosis, yellow fluorescent protein-tagged subunits p67phox and p40phox translocate to granulocyte phagosomes before phagosome internalization and accumulation of a probe for phosphoinositol 3-phosphate. p67phox and p47phox accumulation on nascent and internalized phagosomes does not require p40phox or PI3 kinase activity. Translocation of p40phox to nascent phagosomes requires binding to p67phox but not phosphoinositol 3-phosphate | Homo sapiens | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | subunit p40phox functions primarily to regulate Fcgamma receptor-induced NADPH oxidase activity rather than assembly of the enzyme, and stimulates superoxide production via a phosphoinositol 3-phosphate signal that increases after phagosome internalization | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | subunit p40phox functions primarily to regulate Fcgamma receptor-induced NADPH oxidase activity rather than assembly of the enzyme, and stimulates superoxide production via a phosphoinositol 3-phosphate signal that increases after phagosome internalization | Homo sapiens | ? | - |
? |