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BRENDA support

Literature summary for 1.6.3.1 extracted from

  • Whaley-Connell, A.T.; Morris, E.M.; Rehmer, N.; Yaghoubian, J.C.; Wei, Y.; Hayden, M.R.; Habibi, J.; Stump, C.S.; Sowers, J.R.
    Albumin activation of NAD(P)H oxidase activity is mediated via Rac1 in proximal tubule cells (2007), Am. J. Nephrol., 27, 15-23.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
bovine serum albumin time-dependent increases in NAD(P)H oxidase activity with bovine serum albumin stimulation that is inhibited in a concentration-dependent manner with the HMG-CoA reductase inhibitor rosuvastatin, or with Rac1 inhibitor NSC23766. Following albumin stimulation, Rac1 translocates to plasma membrane for NAD(P)H oxidase activation Didelphis sp.

Organism

Organism UniProt Comment Textmining
Didelphis sp.
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Source Tissue

Source Tissue Comment Organism Textmining
kidney proximal tubule cell Didelphis sp.
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