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Literature summary for 1.6.2.4 extracted from

  • Arinc, E.; Philpot, R.M.
    Preparation and properties of partially purified pulmonary cytochrome P-450 from rabbits (1976), J. Biol. Chem., 251, 3213-3220.
    View publication on PubMed
Search for more literature for 1.6.2.4

General Stability

General Stability Organism
ability to support benzphetamine N-demethylation activity decreased by about 30% after 1 week of storage at -20°C Oryctolagus cuniculus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Oryctolagus cuniculus
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Oryctolagus cuniculus mixed function oxidase system composed of cytochrome P-450, NADPH-cytochrome c reductase and phospholipids, biotransformation of airborne compounds ?
-
 ?

Organism

Organism UniProt Comment Textmining
Oryctolagus cuniculus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Oryctolagus cuniculus

Renatured (Commentary)

Renatured (Comment) Organism
reconstitution of O-deethylation and N-demethylation activity Oryctolagus cuniculus

Source Tissue

Source Tissue Comment Organism Textmining
lung
-
 Oryctolagus cuniculus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Oryctolagus cuniculus

Storage Stability

Storage Stability Organism
-20°C, N2-atmosphere, several weeks Oryctolagus cuniculus
-20°C, under nitrogen, several weeks Oryctolagus cuniculus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2 ferricytochrome c + NADPH
-
 Oryctolagus cuniculus 2 ferrocytochrome c + NADP+ + H+
-
 ?
additional information N-demethylation of benzphetamine Oryctolagus cuniculus ?
-
 ?
additional information O-deethylation of 7-ethoxycoumarin Oryctolagus cuniculus ?
-
 ?
additional information mixed function oxidase system composed of cytochrome P-450, NADPH-cytochrome c reductase and phospholipids, biotransformation of airborne compounds Oryctolagus cuniculus ?
-
 ?