Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Dimethylthetin | - |
Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Rattus norvegicus | 5739 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
epsilon-N-methyl-L-lysine + acceptor + H2O | - |
Rattus norvegicus | formaldehyde + L-lysine + reduced acceptor | - |
? | |
N,N-dimethylglycine + acceptor + H2O | acceptors: 2,6-dichlorophenolindophenol, phenazine methosulfate | Rattus norvegicus | sarcosine + formaldehyde + reduced acceptor | - |
? | |
N,N-dimethylglycine + acceptor + H2O | bound tetrahydrofolate interacts directly with the enzyme and serves as an acceptor for the one-carbon unit produced during the oxidative demethylation of dimethylglycine | Rattus norvegicus | sarcosine + formaldehyde + reduced acceptor | - |
? | |
N-methyl-L-alanine + acceptor + H2O | - |
Rattus norvegicus | formaldehyde + L-alanine + reduced acceptor | - |
? | |
sarcosine + acceptor + H2O | - |
Rattus norvegicus | glycine + formaldehyde + reduced acceptor | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | covalently bound | Rattus norvegicus |