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Literature summary for 1.5.8.2 extracted from

  • Bellamy, H.D.; Lim, L.W.; Mathews, F.S.
    Studies of crystalline trimethyllamine dehydrogenase in three oxidation states and in the presence of substrate and inhibitor (1989), J. Biol. Chem., 264, 11887-11892.
    View publication on PubMed

Crystallization (Commentary)

Crystallization (Comment) Organism
macro-seeding of sitting drops, 6 A resolution Methylophilus methylotrophus

Inhibitors

Inhibitors Comment Organism Structure
Tetramethylammonium chloride
-
Methylophilus methylotrophus

Metals/Ions

Metals/Ions Comment Organism Structure
Fe 4Fe-4S-center Methylophilus methylotrophus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
trimethylamine + H2O + electron transferring flavoprotein Methylophilus methylotrophus
-
dimethylamine + formaldehyde + reduced electron transferring flavoprotein
-
?
trimethylamine + H2O + electron transferring flavoprotein Methylophilus methylotrophus W3A1
-
dimethylamine + formaldehyde + reduced electron transferring flavoprotein
-
?

Organism

Organism UniProt Comment Textmining
Methylophilus methylotrophus
-
-
-
Methylophilus methylotrophus W3A1
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
cell culture
-
Methylophilus methylotrophus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
trimethylamine + H2O + electron transferring flavoprotein
-
Methylophilus methylotrophus dimethylamine + formaldehyde + reduced electron transferring flavoprotein
-
?
trimethylamine + H2O + electron transferring flavoprotein
-
Methylophilus methylotrophus W3A1 dimethylamine + formaldehyde + reduced electron transferring flavoprotein
-
?

Cofactor

Cofactor Comment Organism Structure
FMN
-
Methylophilus methylotrophus