Crystallization (Comment) | Organism |
---|---|
hanging drop method | Escherichia coli |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-proline + acceptor + H2O | Escherichia coli | PutA flavoprotein plays multiple roles in proline catabolism by functioning as a membrane-associated bi-functional enzyme and a transcriptional repressor of proline utilization genes | (S)-1-pyrroline-5-carboxylate + reduced acceptor | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | P09546 | PutA669, corresponding to the N-terminal 669 residues of the 1320-amino acid PutA polypeptide chain | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-proline + acceptor + H2O | PutA flavoprotein plays multiple roles in proline catabolism by functioning as a membrane-associated bi-functional enzyme and a transcriptional repressor of proline utilization genes | Escherichia coli | (S)-1-pyrroline-5-carboxylate + reduced acceptor | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | domain-swapped dimer with each subunit comprising three domains: a helical dimerization arm, a 120-residue domain containing a three-helix bundle similar to that in the helix-turn-helix superfamily of DNA-binding proteins and a beta/alpha-barrel PRODH domain with a bound lactate inhibitor | Escherichia coli |
Synonyms | Comment | Organism |
---|---|---|
PutA flavoprotein | - |
Escherichia coli |