Application | Comment | Organism |
---|---|---|
medicine | alterations in the levels of spermine synthase SMS and spermine oxidase SMOX have previously been observed in brains of suicide completers. SMS and SMOX display several promoter haplotypes, without consistent effects of haplotype on expression levels in either the brain or in reporter gene assays performed in three different cell lines. There are no overall effects of epigenetic factors in determining expression, with the exception of a relationship between CpG methylation at one site in the promoter of SMOX and its expression in Brodmann area 8/9. The genetic and epigenetic factors examined in this study show little influence on the expression levels of SMS and SMOX | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
SMOX | - |
Homo sapiens |