Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
KCl | dihydrofolate reductase hvDHFR1 and hvDHFR2 unfold at KCl concentrations below 0.5 M. Above 1 M, the KCl dependence of the dihydrofolate reductase activities can be attributed to the effect of salt on substrate affinity | Haloferax volcanii |
Organic Solvent | Comment | Organism |
---|---|---|
urea | dihydrofolate reductase hvDHFR1 is ,12 kcal/mol more stable to urea denaturation than dihydrofolate reductase hvDHFR2. NaCl, KCl, and CsCl enhance the stability to urea denaturation | Haloferax volcanii |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Haloferax volcanii | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
hvDHFR1 | - |
Haloferax volcanii |
hvDHFR2 | - |
Haloferax volcanii |