Literature summary for 1.5.1.20 extracted from

Chen, Z.; Liu, Y.; Zhang, D.; Liu, Z.; Wang, P.; Zhou, D.; Zhao, T.; Wang, T.; Xu, H.; Li, S.; Feng, G.; He, L.; Yu, L.
C677T methylenetetrahydrofolate reductase gene polymorphisms in bipolar disorder: an association study in the Chinese population and a meta-analysis of genetic association studies (2009), Neurosci. Lett., 449, 48-51.

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Application

Application	Comment	Organism
medicine	No significant difference is found in either Mthfr allele frequencies or genotype distribution between patients with bipolar disorder and controls in an association study in the Chinese population. The meta-analysis result shows no significant association between Mthfr C677T and bipolar disorder	Homo sapiens

Protein Variants

Protein Variants	Comment	Organism
C677T	no significant association between Mthfr mutation C677T and bipolar disorder	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	patients with bipolar disorder	-

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Release 2023.1 (January 2023)