Literature summary for 1.5.1.20 extracted from

Smulders, Y.M.; Smith, D.E.; Kok, R.M.; Teerlink, T.; Gellekink, H.; Vaes, W.H.; Stehouwer, C.D.; Jakobs, C.
Red blood cell folate vitamer distribution in healthy subjects is determined by the methylenetetrahydrofolate reductase C677T polymorphism and by the total folate status (2007), J. Nutr. Biochem., 18, 693-699.

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Protein Variants

Protein Variants	Comment	Organism
additional information	the MTHFR C677T genotype is the dominant determinant of nonmethylfolate accumulation in red blood cells	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
erythrocyte	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
5,10-methylenetetrahydrofolate + reduced acceptor	-	Homo sapiens	5-methyltetrahydrofolate + oxidized acceptor	-	?

Synonyms

Synonyms	Comment	Organism
methylenetetrahydrofolate reductase	-	Homo sapiens
MTHFR	-	Homo sapiens

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Release 2023.1 (January 2023)