Protein Variants | Comment | Organism |
---|---|---|
T34A | complete blocking of phosphorylation of enzyme. Mutant enzyme is more active than wild-type and less sensitive to inhibition by S-adenosylmethionie | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
S-adenosyl-L-methionine | allosteric inhibition and control of phosphorylation | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
recombinant enzyme, expression in Escherichia coli, Baculovirus system, or HEK293 cells | - |
Posttranslational Modification | Comment | Organism |
---|---|---|
phosphoprotein | treatment by alkaline phosphatase removes seven phosphoryl groups from enzyme. Treated enzyme is more active than native enzyme and less sensitive to inhibition by S-adenosylmethionie | Homo sapiens |