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Literature summary for 1.5.1.20 extracted from

  • Varalakshmi, K.; Savithri, H.S.; Rao, N.A.
    Identification of amino acid residues essential for enzyme activity of sheep liver 5,10-methylenetetrahydrofolate reductase (1986), Biochem. J., 236, 295-298.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
diethyldicarbonate 20 mM NADP+ and 20 mM NAD+ partially protected the enzyme against inactivation whereas 20 mM nicotinamide gives complete protection Ovis aries
additional information residues essential for enzyme activity: arginine, histidine, tryptophan Ovis aries
N-bromosuccinimide inactivates the enzyme by modification of tryptophan Ovis aries
Phenylglyoxal
-
Ovis aries

Organism

Organism UniProt Comment Textmining
Ovis aries
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Ovis aries
-