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Literature summary for 1.5.1.2 extracted from
- The p53-induced gene-6 (proline oxidase) mediates apoptosis through a calcineurin-dependent pathway (2005), J. Biol. Chem., 280, 29346-29354.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | mediating apoptosis in tumor cells | Homo sapiens |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| proline oxidase cDNA is cloned into the pAdtrack vector, it is used to generate a recombinant adenovirus for transfection | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-proline + NAD(P)+ | Homo sapiens | - |
1-pyrroline-5-carboxylate + NAD(P)H + H+ | - |
r |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| DLD-1 cell | colon adenocarcinoma cell | Homo sapiens | - |
| non-small cell lung cancer cell | H1299 | Homo sapiens | - |
| ovary cell line | TOV-21G | Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-proline + NAD(P)+ | - |
Homo sapiens | 1-pyrroline-5-carboxylate + NAD(P)H + H+ | - |
r | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| POX | - |
Homo sapiens |
| proline oxidase | - |
Homo sapiens |
| pyrroline-5-carboxylate reductase | - |
Homo sapiens |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NAD(P)H | - |
Homo sapiens | |
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Release 2023.1 (January 2023)
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