Inhibitors | Comment | Organism | Structure |
---|---|---|---|
D-lactate | weak | Mercenaria mercenaria | |
L-lactate | weak | Mercenaria mercenaria | |
meso-Alanopine | weak | Mercenaria mercenaria | |
succinate | weak | Mercenaria mercenaria |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.38 | - |
pyruvate | - |
Mercenaria mercenaria | |
2.5 | - |
2-oxobutyrate | - |
Mercenaria mercenaria | |
11.9 | - |
glyoxylate | - |
Mercenaria mercenaria | |
15 | - |
L-2-aminobutyrate | - |
Mercenaria mercenaria | |
15.1 | - |
L-Ala | - |
Mercenaria mercenaria | |
20 | - |
L-Val | - |
Mercenaria mercenaria | |
23 | - |
L-Cys | - |
Mercenaria mercenaria | |
28 | - |
L-Ala | - |
Mercenaria mercenaria | |
110 | - |
L-Thr | - |
Mercenaria mercenaria | |
247 | - |
L-Ser | - |
Mercenaria mercenaria | |
291 | - |
Gly | - |
Mercenaria mercenaria |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Mercenaria mercenaria | the enzyme functions as the terminal dehydrogenase of glycolysis and has a role in maintaining energy production under the stresses of environmental or functional anoxia | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mercenaria mercenaria | - |
- |
- |
Purification (Comment) | Organism |
---|---|
partial | Mercenaria mercenaria |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
gill | - |
Mercenaria mercenaria | - |
mantle | - |
Mercenaria mercenaria | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Gly + pyruvate + NADH | at 69% of the activity with L-Ala | Mercenaria mercenaria | Strombine + NAD+ + H2O | - |
? | |
L-2-Aminobutyrate + pyruvate + NADH | at 94% of the activity with L-Ala | Mercenaria mercenaria | ? | - |
? | |
L-Ala + 2-oxobutanoate + NADH | at 22% the activity with pyruvate | Mercenaria mercenaria | ? | - |
? | |
L-Ala + glyoxylate + NADH | at 44% the activity with pyruvate | Mercenaria mercenaria | ? | - |
? | |
L-Ala + pyruvate + NADH | - |
Mercenaria mercenaria | 2,2'-Iminodipropanoate + NAD+ + H2O | - |
? | |
L-Cys + pyruvate + NADH | at 90% of the activity with L-Ala | Mercenaria mercenaria | ? | - |
? | |
L-Ser + pyruvate + NADH | at 90% of the activity with L-Ala | Mercenaria mercenaria | ? | - |
? | |
L-Thr + pyruvate + NADH | at 62% of the activity with L-Ala | Mercenaria mercenaria | ? | - |
? | |
L-Val + pyruvate + NADH | at 65% of the activity with L-Ala | Mercenaria mercenaria | ? | - |
? | |
additional information | the enzyme functions as the terminal dehydrogenase of glycolysis and has a role in maintaining energy production under the stresses of environmental or functional anoxia | Mercenaria mercenaria | ? | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Mercenaria mercenaria | |
NADH | - |
Mercenaria mercenaria |