KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | - |
Pecten maximus | |
additional information | - |
additional information | - |
Calliactis parasitica | |
additional information | - |
additional information | - |
Arctica islandica | |
0.1 | - |
D-octopine | brain enzyme | Sepia officinalis | |
0.6 | - |
pyruvate | pyruvate | Mytilus edulis | |
0.6 | - |
pyruvate | brain enzyme | Sepia officinalis | |
0.6 | - |
pyruvate | oxaloacetate | Mytilus edulis | |
0.8 | - |
pyruvate | - |
Mytilus edulis | |
0.8 | - |
pyruvate | - |
Cerastoderma edule | |
0.8 | - |
pyruvate | - |
Glycymeris glycymeris | |
0.9 | - |
Arg | - |
Mytilus edulis | |
0.9 | - |
Arg | oxaloacetate | Cerastoderma edule | |
0.9 | - |
Arg | D-octopine, mantle enzyme | Sepia officinalis | |
1 | - |
oxaloacetate | - |
Glycymeris glycymeris | |
1.4 | - |
L-Arg | pyruvate, mantle enzyme | Sepia officinalis | |
1.4 | - |
L-Arg | with pyruvate as cosubstrate | Mytilus edulis | |
1.5 | - |
D-octopine | - |
Pecten maximus | |
1.5 | - |
D-octopine | - |
Glycymeris glycymeris | |
1.6 | - |
oxaloacetate | brain enzyme | Sepia officinalis | |
1.8 | - |
Lys | - |
Mytilus edulis | |
1.8 | - |
Lys | L-Arg, with pyruvate as cosubstrate | Glycymeris glycymeris | |
2 | - |
D-octopine | L-Arg, with pyruvate as cosubstrate, brain enzyme | Sepia officinalis | |
2.2 | - |
L-Arg | with 2-ketobutanoate as cosubstrate | Glycymeris glycymeris | |
2.4 | - |
NADH | - |
Glycymeris glycymeris | |
2.5 | - |
Arg | L-Arg, with oxaloacetate as cosubstrate | Mytilus edulis | |
2.5 | - |
Arg | L-Lys, brain enzyme | Sepia officinalis | |
2.6 | - |
oxaloacetate | D-lysopine, brain enzyme | Sepia officinalis | |
2.6 | - |
oxaloacetate | mantle enzyme | Sepia officinalis | |
3 | - |
L-Arg | with pyruvate as cosubstrate | Cerastoderma edule | |
3.1 | - |
pyruvate | D-octopine | Mytilus edulis | |
3.2 | - |
D-lysopine | - |
Glycymeris glycymeris | |
3.2 | - |
D-lysopine | - |
Sepia officinalis | |
3.3 | - |
L-Lys | - |
Mytilus edulis | |
3.7 | - |
L-Arg | L-Lys | Glycymeris glycymeris | |
3.7 | - |
L-Arg | with 2-ketobutanoate as cosubstrate | Mytilus edulis | |
3.8 | - |
L-Arg | with 2-ketobutanoate as cosubstrate | Cerastoderma edule | |
4 | - |
L-Arg | with oxaloacetate as cosubstrate | Cerastoderma edule | |
5 | - |
L-Arg | with oxaloacetate as cosubstrate | Mytilus edulis | |
5.2 | - |
D-octopine | - |
Cerastoderma edule | |
5.3 | - |
L-Arg | with 2-ketobutanoate as cosubstrate, brain enzyme | Sepia officinalis | |
5.5 | - |
L-Arg | with pyruvate as cosubstrate, mantle enzyme | Sepia officinalis | |
5.8 | - |
NADH | - |
Mytilus edulis | |
6.1 | - |
L-Lys | mantle enzyme | Sepia officinalis | |
6.1 | - |
L-Lys | 2-ketobutanoate, brain enzyme | Sepia officinalis | |
6.2 | - |
2-oxobutanoate | - |
Cerastoderma edule | |
6.2 | - |
L-Arg | with 2-oxobutanoate as cosubstrate, mantle enzyme | Sepia officinalis | |
6.4 | - |
D-lysopine | - |
Mytilus edulis | |
7.3 | - |
2-oxobutanoate | - |
Mytilus edulis | |
7.8 | - |
2-oxobutanoate | mantle enzyme | Sepia officinalis | |
8 | - |
L-Arg | 2-ketobutanoate | Glycymeris glycymeris | |
8 | - |
L-Arg | with oxaloacetate as cosubstrate, mantle enzyme | Sepia officinalis | |
12 | - |
L-Arg | with oxaloacetate as cosubstrate, brain enzyme | Sepia officinalis | |
13 | - |
NADH | - |
Cerastoderma edule | |
15 | - |
NADH | brain enzyme | Sepia officinalis | |
18 | - |
NADH | mantle enzyme | Sepia officinalis | |
25 | - |
L-Orn | brain enzyme | Sepia officinalis | |
28 | - |
L-Orn | - |
Cerastoderma edule | |
48 | - |
NAD+ | brain enzyme | Sepia officinalis | |
65 | - |
NAD+ | - |
Mytilus edulis | |
75 | - |
NAD+ | - |
Glycymeris glycymeris | |
110 | - |
NAD+ | NAD+ | Cerastoderma edule | |
110 | - |
NAD+ | mantle enzyme | Sepia officinalis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Mytilus edulis | the evolutionary development of the enzyme appears to have led from a broadly specific imino acid dehydrogenase in sea anemones to enzymes increasingly specific for the substrate L-Arg, and pyruvate only. This trend is correlated with an increasing importance of the enzyme in glycolytic redox balance in working muscle and an increased dependence on muscle arginine phosphate reserves for rapid energy generation in higher invertebrate groups | ? | - |
? | |
additional information | Cerastoderma edule | the evolutionary development of the enzyme appears to have led from a broadly specific imino acid dehydrogenase in sea anemones to enzymes increasingly specific for the substrate L-Arg, and pyruvate only. This trend is correlated with an increasing importance of the enzyme in glycolytic redox balance in working muscle and an increased dependence on muscle arginine phosphate reserves for rapid energy generation in higher invertebrate groups | ? | - |
? | |
additional information | Glycymeris glycymeris | the evolutionary development of the enzyme appears to have led from a broadly specific imino acid dehydrogenase in sea anemones to enzymes increasingly specific for the substrate L-Arg, and pyruvate only. This trend is correlated with an increasing importance of the enzyme in glycolytic redox balance in working muscle and an increased dependence on muscle arginine phosphate reserves for rapid energy generation in higher invertebrate groups | ? | - |
? | |
additional information | Sepia officinalis | the evolutionary development of the enzyme appears to have led from a broadly specific imino acid dehydrogenase in sea anemones to enzymes increasingly specific for the substrate L-Arg, and pyruvate only. This trend is correlated with an increasing importance of the enzyme in glycolytic redox balance in working muscle and an increased dependence on muscle arginine phosphate reserves for rapid energy generation in higher invertebrate groups | ? | - |
? | |
additional information | Sepia officinalis | major physiological role in glycolytic energy poduction during burst swimming | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Arctica islandica | - |
- |
- |
Calliactis parasitica | - |
- |
- |
Cerastoderma edule | - |
- |
- |
Glycymeris glycymeris | - |
- |
- |
Mytilus edulis | - |
- |
- |
Pecten maximus | - |
- |
- |
Sepia officinalis | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adductor | - |
Pecten maximus | - |
adductor | - |
Mytilus edulis | - |
adductor | - |
Cerastoderma edule | - |
brain | - |
Sepia officinalis | - |
foot muscle | - |
Mytilus edulis | - |
foot muscle | - |
Cerastoderma edule | - |
foot muscle | - |
Glycymeris glycymeris | - |
foot muscle | - |
Arctica islandica | - |
mantle muscle | - |
Calliactis parasitica | - |
mantle muscle | - |
Sepia officinalis | - |
pedal muscle | - |
Calliactis parasitica | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Canavanine + pyruvate + NADH | - |
Mytilus edulis | N2-(D-1-Carboxyethyl)-canavanine + NAD+ + H2O | - |
? | |
Canavanine + pyruvate + NADH | - |
Calliactis parasitica | N2-(D-1-Carboxyethyl)-canavanine + NAD+ + H2O | - |
? | |
Canavanine + pyruvate + NADH | - |
Cerastoderma edule | N2-(D-1-Carboxyethyl)-canavanine + NAD+ + H2O | - |
? | |
Canavanine + pyruvate + NADH | - |
Glycymeris glycymeris | N2-(D-1-Carboxyethyl)-canavanine + NAD+ + H2O | - |
? | |
Canavanine + pyruvate + NADH | - |
Sepia officinalis | N2-(D-1-Carboxyethyl)-canavanine + NAD+ + H2O | - |
? | |
Canavanine + pyruvate + NADH | - |
Arctica islandica | N2-(D-1-Carboxyethyl)-canavanine + NAD+ + H2O | - |
? | |
Homoarginine + pyruvate + NADH | - |
Mytilus edulis | N2-(D-1-Carboxyethyl)-homoarginine + NAD+ + H2O | - |
? | |
Homoarginine + pyruvate + NADH | - |
Calliactis parasitica | N2-(D-1-Carboxyethyl)-homoarginine + NAD+ + H2O | - |
? | |
Homoarginine + pyruvate + NADH | - |
Cerastoderma edule | N2-(D-1-Carboxyethyl)-homoarginine + NAD+ + H2O | - |
? | |
Homoarginine + pyruvate + NADH | - |
Glycymeris glycymeris | N2-(D-1-Carboxyethyl)-homoarginine + NAD+ + H2O | - |
? | |
Homoarginine + pyruvate + NADH | - |
Sepia officinalis | N2-(D-1-Carboxyethyl)-homoarginine + NAD+ + H2O | - |
? | |
Homoarginine + pyruvate + NADH | - |
Arctica islandica | N2-(D-1-Carboxyethyl)-homoarginine + NAD+ + H2O | - |
? | |
L-Arg + 2-oxobutanoate + NADH | - |
Mytilus edulis | N2-(D-2-Carboxypropyl)-L-Arg + NAD+ + H2O | - |
? | |
L-Arg + 2-oxobutanoate + NADH | - |
Calliactis parasitica | N2-(D-2-Carboxypropyl)-L-Arg + NAD+ + H2O | - |
? | |
L-Arg + 2-oxobutanoate + NADH | - |
Cerastoderma edule | N2-(D-2-Carboxypropyl)-L-Arg + NAD+ + H2O | - |
? | |
L-Arg + 2-oxobutanoate + NADH | - |
Glycymeris glycymeris | N2-(D-2-Carboxypropyl)-L-Arg + NAD+ + H2O | - |
? | |
L-Arg + 2-oxobutanoate + NADH | - |
Sepia officinalis | N2-(D-2-Carboxypropyl)-L-Arg + NAD+ + H2O | - |
? | |
L-Arg + 2-oxobutanoate + NADH | - |
Arctica islandica | N2-(D-2-Carboxypropyl)-L-Arg + NAD+ + H2O | - |
? | |
L-Arg + oxaloacetate + NADH | - |
Mytilus edulis | ? | - |
? | |
L-Arg + oxaloacetate + NADH | - |
Calliactis parasitica | ? | - |
? | |
L-Arg + oxaloacetate + NADH | - |
Cerastoderma edule | ? | - |
? | |
L-Arg + oxaloacetate + NADH | - |
Glycymeris glycymeris | ? | - |
? | |
L-Arg + oxaloacetate + NADH | - |
Sepia officinalis | ? | - |
? | |
L-Arg + oxaloacetate + NADH | - |
Arctica islandica | ? | - |
? | |
L-Arg + pyruvate + NADH | - |
Cerastoderma edule | N2-(D-1-carboxyethyl)-L-Arg + NAD+ + H2O | - |
? | |
L-Arg + pyruvate + NADH | - |
Glycymeris glycymeris | N2-(D-1-carboxyethyl)-L-Arg + NAD+ + H2O | - |
? | |
L-Arg + pyruvate + NADH | - |
Sepia officinalis | N2-(D-1-carboxyethyl)-L-Arg + NAD+ + H2O | - |
? | |
L-Arg + pyruvate + NADH | - |
Arctica islandica | N2-(D-1-carboxyethyl)-L-Arg + NAD+ + H2O | - |
? | |
L-Arg + pyruvate + NADH | r | Pecten maximus | N2-(D-1-carboxyethyl)-L-Arg + NAD+ + H2O | - |
? | |
L-Arg + pyruvate + NADH | r | Mytilus edulis | N2-(D-1-carboxyethyl)-L-Arg + NAD+ + H2O | - |
? | |
L-Arg + pyruvate + NADH | r | Calliactis parasitica | N2-(D-1-carboxyethyl)-L-Arg + NAD+ + H2O | - |
? | |
L-Lys + pyruvate + NADH | - |
Sepia officinalis | Lysopine + NAD+ + H2O | - |
? | |
L-Lys + pyruvate + NADH | no activity | Pecten maximus | Lysopine + NAD+ + H2O | - |
? | |
L-Lys + pyruvate + NADH | no activity | Cerastoderma edule | Lysopine + NAD+ + H2O | - |
? | |
L-Lys + pyruvate + NADH | no activity | Arctica islandica | Lysopine + NAD+ + H2O | - |
? | |
L-Lys + pyruvate + NADH | r | Mytilus edulis | Lysopine + NAD+ + H2O | - |
? | |
L-Lys + pyruvate + NADH | r | Calliactis parasitica | Lysopine + NAD+ + H2O | - |
? | |
L-Lys + pyruvate + NADH | r | Glycymeris glycymeris | Lysopine + NAD+ + H2O | - |
? | |
additional information | the evolutionary development of the enzyme appears to have led from a broadly specific imino acid dehydrogenase in sea anemones to enzymes increasingly specific for the substrate L-Arg, and pyruvate only. This trend is correlated with an increasing importance of the enzyme in glycolytic redox balance in working muscle and an increased dependence on muscle arginine phosphate reserves for rapid energy generation in higher invertebrate groups | Mytilus edulis | ? | - |
? | |
additional information | the evolutionary development of the enzyme appears to have led from a broadly specific imino acid dehydrogenase in sea anemones to enzymes increasingly specific for the substrate L-Arg, and pyruvate only. This trend is correlated with an increasing importance of the enzyme in glycolytic redox balance in working muscle and an increased dependence on muscle arginine phosphate reserves for rapid energy generation in higher invertebrate groups | Cerastoderma edule | ? | - |
? | |
additional information | the evolutionary development of the enzyme appears to have led from a broadly specific imino acid dehydrogenase in sea anemones to enzymes increasingly specific for the substrate L-Arg, and pyruvate only. This trend is correlated with an increasing importance of the enzyme in glycolytic redox balance in working muscle and an increased dependence on muscle arginine phosphate reserves for rapid energy generation in higher invertebrate groups | Glycymeris glycymeris | ? | - |
? | |
additional information | the evolutionary development of the enzyme appears to have led from a broadly specific imino acid dehydrogenase in sea anemones to enzymes increasingly specific for the substrate L-Arg, and pyruvate only. This trend is correlated with an increasing importance of the enzyme in glycolytic redox balance in working muscle and an increased dependence on muscle arginine phosphate reserves for rapid energy generation in higher invertebrate groups | Sepia officinalis | ? | - |
? | |
additional information | major physiological role in glycolytic energy poduction during burst swimming | Sepia officinalis | ? | - |
? | |
Orn + pyruvate + NADH | - |
Mytilus edulis | N2-(D-1-Carboxyethyl)-L-Orn + NAD+ + H2O | - |
? | |
Orn + pyruvate + NADH | - |
Calliactis parasitica | N2-(D-1-Carboxyethyl)-L-Orn + NAD+ + H2O | - |
? | |
Orn + pyruvate + NADH | - |
Cerastoderma edule | N2-(D-1-Carboxyethyl)-L-Orn + NAD+ + H2O | - |
? | |
Orn + pyruvate + NADH | - |
Glycymeris glycymeris | N2-(D-1-Carboxyethyl)-L-Orn + NAD+ + H2O | - |
? | |
Orn + pyruvate + NADH | no activity | Pecten maximus | N2-(D-1-Carboxyethyl)-L-Orn + NAD+ + H2O | - |
? | |
Orn + pyruvate + NADH | no activity | Arctica islandica | N2-(D-1-Carboxyethyl)-L-Orn + NAD+ + H2O | - |
? | |
Orn + pyruvate + NADH | activity with brain enzyme, no activity with mantle enzyme | Sepia officinalis | N2-(D-1-Carboxyethyl)-L-Orn + NAD+ + H2O | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADH | - |
Pecten maximus | |
NADH | - |
Mytilus edulis | |
NADH | - |
Calliactis parasitica | |
NADH | - |
Cerastoderma edule | |
NADH | - |
Glycymeris glycymeris | |
NADH | - |
Sepia officinalis | |
NADH | - |
Arctica islandica |