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Literature summary for 1.4.9.2 extracted from

  • Roujeinikova, A.; Hothi, P.; Masgrau, L.; Sutcliffe, M.J.; Scrutton, N.S.; Leys, D.
    New insights into the reductive half-reaction mechanism of aromatic amine dehydrogenase revealed by reaction with carbinolamine substrates (2007), J. Biol. Chem., 282, 23766-23777.
    View publication on PubMed
Search for more literature for 1.4.9.2

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
12000
-
 2 * 40000 + 2 * 12000 Alcaligenes faecalis
40000
-
 2 * 40000 + 2 * 12000 Alcaligenes faecalis

Organism

Organism UniProt Comment Textmining
Alcaligenes faecalis
-
-
-
Alcaligenes faecalis IFO 14479
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Alcaligenes faecalis

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
aromatic amines + acceptor + H2O specific for phenylethylamines, but also reacts to a lesser extent with primary aliphatic amines Alcaligenes faecalis ? + reduced acceptor + NH3
-
 ?
aromatic amines + acceptor + H2O specific for phenylethylamines, but also reacts to a lesser extent with primary aliphatic amines Alcaligenes faecalis IFO 14479 ? + reduced acceptor + NH3
-
 ?
benzylamine + H2O + 2,6-dichlorophenol
-
 Alcaligenes faecalis ? + NH3 + reduced 2,6-dichlorophenol indophenol
-
 ?
benzylamine + H2O + 2,6-dichlorophenol
-
 Alcaligenes faecalis IFO 14479 ? + NH3 + reduced 2,6-dichlorophenol indophenol
-
 ?
beta-phenylethylamine + H2O + 2,6-dichlorophenolindophenol
-
 Alcaligenes faecalis phenylacetaldehyde + NH3 + reduced 2,6-dichlorophenolindophenol
-
 ?
beta-phenylethylamine + H2O + 2,6-dichlorophenolindophenol
-
 Alcaligenes faecalis IFO 14479 phenylacetaldehyde + NH3 + reduced 2,6-dichlorophenolindophenol
-
 ?
tyramine + H2O + 2,6-dichlorophenol indophenol
-
 Alcaligenes faecalis 4-hydroxyphenylacetaldehyde + NH3 + reduced 2,6-dichlorophenol indophenol
-
 ?
tyramine + H2O + 2,6-dichlorophenol indophenol
-
 Alcaligenes faecalis IFO 14479 4-hydroxyphenylacetaldehyde + NH3 + reduced 2,6-dichlorophenol indophenol
-
 ?

Subunits

Subunits Comment Organism
heterotetramer 2 * 40000 + 2 * 12000 Alcaligenes faecalis

Synonyms

Synonyms Comment Organism
AADH
-
 Alcaligenes faecalis
aromatic amine dehydrogenase
-
 Alcaligenes faecalis

Cofactor

Cofactor Comment Organism Structure
tryptophan tryptophylquinone two molecules per enzyme, tryptophan tryptophylquinone reduction is about 80 times more rapid with tryptamine compared to beta-phenylethylamine Alcaligenes faecalis