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Literature summary for 1.4.7.1 extracted from

  • Kissen, R.; Winge, P.; Tran, D.H.; Joerstad, T.S.; Stoerseth, T.R.; Christensen, T.; Bones, A.M.
    Transcriptional profiling of an Fd-GOGAT1/GLU1 mutant in Arabidopsis thaliana reveals a multiple stress response and extensive reprogramming of the transcriptome (2010), BMC Genomics, 11, 190.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
gene glu1 or gls1, genome wide microarray analysis of the transcriptional reprogramming, overview Arabidopsis thaliana

Protein Variants

Protein Variants Comment Organism
additional information knockout mutant glu1-2, with a T-DNA insertion in the Fd-GOGAT1, lacks expression of Fd-GOGAT1, transcriptional profiling of glu1-2 showing activation of multiple stress responses, mimicking cold, heat, drought and oxidative stress, overview. NMR analysis of glu1-2 mutant leaves and roots reveal differences in amino acid contents compared to the wild-type, overview Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2 L-glutamate + 2 oxidized ferredoxin Arabidopsis thaliana
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L-glutamine + 2-oxoglutarate + 2 reduced ferredoxin + 2 H+
-
?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana Q9ZNZ7
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-

Source Tissue

Source Tissue Comment Organism Textmining
leaf
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Arabidopsis thaliana
-
additional information Fd-GOGAT1 is more highly expressed in leaves than in roots Arabidopsis thaliana
-
root
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Arabidopsis thaliana
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2 L-glutamate + 2 oxidized ferredoxin
-
Arabidopsis thaliana L-glutamine + 2-oxoglutarate + 2 reduced ferredoxin + 2 H+
-
?

Synonyms

Synonyms Comment Organism
Fd-dependent glutamate synthase
-
Arabidopsis thaliana
Fd-GOGAT1
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Arabidopsis thaliana
ferredoxin-dependent glutamate synthase
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Arabidopsis thaliana
Glu1
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Arabidopsis thaliana

Cofactor

Cofactor Comment Organism Structure
Ferredoxin
-
Arabidopsis thaliana

General Information

General Information Comment Organism
metabolism Glu1 is involved in the primary nitrogen assimilation, primary nitrogen assimilation and glutamate metabolism overview. Metabolic profiling and gene expression profiling in glu1-2 knockout mutant, most significantly affected pathways in the Glu1 knockout mutant glu1-2, photosynthesis, photorespiratory cycle and chlorophyll biosynthesis show an overall downregulation in glu1-2 leaves in accordance with their slight chlorotic phenotype, numerous other responsive genes linked to a number of different stresses/stimuli are induced in glu1-2 leaves, very detailed overview Arabidopsis thaliana