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Literature summary for 1.4.4.2 extracted from
- Glycine cleavage enzyme complex: molecular cloning and expression of the H-protein cDNA from cultured human skin fibroblasts (2011), Biochem. Cell Biol., 89, 299-307.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Pichia pastoris strain GS115 | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| glycine + H-protein-lipoyllysine | Homo sapiens | - |
H-protein-S-aminomethyldihydrolipoyllysine + CO2 | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | P23434 | - |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| Ni-NTA column chromatography | Homo sapiens |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| fibroblast | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| glycine + H-protein-lipoyllysine | - |
Homo sapiens | H-protein-S-aminomethyldihydrolipoyllysine + CO2 | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| GDC | - |
Homo sapiens |
| glycine cleavage enzyme complex | - |
Homo sapiens |
| H-protein | - |
Homo sapiens |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | the H-protein interacts with the L-protein, which is also part of the L-ketoglutarate dehydrogenase complex | Homo sapiens |
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Release 2023.1 (January 2023)
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