Cloned (Comment) | Organism |
---|---|
expression in Pichia pastoris | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(aminomethyl)trimethylsilane | - |
Homo sapiens | |
5-(aminomethyl)-3-aryl-2-oxazolidinones | - |
Homo sapiens | |
Pargyline | MAO-B sensitive | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | - |
Homo sapiens | |
additional information | - |
additional information | - |
Bos taurus | |
0.33 | - |
O2 | - |
Homo sapiens | |
0.5 | - |
benzylamine | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrial outer membrane | - |
Homo sapiens | 5741 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
59163 | - |
x * 59163, electrospray mass spectroscopy, including one covalent FAD, MAO-B | Homo sapiens |
59474 | - |
x * 60000, SDS-PAGE, x * 59474, electrospray mass spectroscopy, including one covalent FAD, MAO-B | Homo sapiens |
60000 | - |
x * 60000, SDS-PAGE, x * 59474, electrospray mass spectroscopy, including one covalent FAD, MAO-B | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
RCH2NH2 + H2O + O2 | Bos taurus | responsible for the catabolism of various biogenic amine neurotransmitters as well as for the metabolism of certain exogenous amines | RCHO + NH3 + H2O2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Homo sapiens | - |
liver | - |
Bos taurus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Homo sapiens |
additional information | - |
- |
Bos taurus |
Storage Stability | Organism |
---|---|
considerable stability to handling and storage, MAO-B | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
benzylamine + H2O + O2 | - |
Homo sapiens | benzaldehyde + NH3 + H2O2 | - |
? | |
RCH2NH2 + H2O + O2 | responsible for the catabolism of various biogenic amine neurotransmitters as well as for the metabolism of certain exogenous amines | Bos taurus | RCHO + NH3 + H2O2 | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 59163, electrospray mass spectroscopy, including one covalent FAD, MAO-B | Homo sapiens |
? | x * 60000, SDS-PAGE, x * 59474, electrospray mass spectroscopy, including one covalent FAD, MAO-B | Homo sapiens |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
10 | - |
benzylamine | recombinant MAO-B | Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
flavin | 1 mol FAD per mol of MAO B is covalently bound by an 8-alpha-S-cysteinyl 397 linkage | Homo sapiens |